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Nutrition, Metabolism, and Body Temperature, Lecture notes of Anatomy

An overview of nutrition, metabolism, and body temperature. It explains the process of nutrition, the six major classes of nutrients, and the functions of carbohydrates, lipids, proteins, and vitamins. It also discusses the recommended amounts of each nutrient and the consequences of their deficiency or excess. suitable for students studying anatomy and physiology or nutrition.

Typology: Lecture notes

2021/2022

Available from 11/04/2022

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NUTRITION, METABOLISM, AND BODY TEMP.
1st YR | ANAPHY
NUTRITION is the process by which food is
taken into and used by the body; it includes
digestion, absorption, transport, and
metabolism.
The study of nutrition involves the study
of the food and drink requirements for
normal body function.
Nutrients are the chemicals taken into
the body that provide energy and
building blocks for new molecules.
NUTRIENTS IS DIVIDED TO (6)
MAJOR CLASSES:
1. CARBOHYDRATES
2. LIPIDS
3. PROTEINS
4. VITAMINS
5. MINERALS
6. WATER
A balanced diet consists of enough
nutrients in the correct proportions to
support normal body functions.
Essential nutrients are nutrients that
must be ingested because the body
cannot manufacture them- or it CANNOT
manufacture them in adequate
amounts.
The essential nutrients include certain
amino acids, fatty acids, most vitamins,
minerals, water, and some
carbohydrates.
CARBOHYDRATES
Contain C, H, O
H:O is a 2:1 ratio
Example: C6H12O6
Include monosaccharides,
disaccharides, and polysaccharides.
- MONOSACCHARIDES simple sugar (1
sugar)
Example: glucose and fructose
- DISACCHARIDE two (2) sugars
Examples: glucose + fructose = sucrose
glucose + galactose = lactose
- POLYSACCHARIDE many sugars
Examples: starch, grain, vegetables,
glycogen
TYPES OF CARBOHYDRATES
1. Simple no nutritional value; cause
weight gain
Examples: candy and soft drinks
Recommended amount: sparingly
2. Complex fiber helps decrease colon
cancer and heart disease.
Examples: whole grains, pastas, rice,
bread.
Recommended amount: at every meal
FUNCTIONS OF CARBOHYDRATES
- Short-term energy storage
- Converted to glucose quickly
- Glucose is used to make ATP
(energy)
- Brain cells require glucose
LIPIDS
LIPIDS - totally or partially insoluble in
water.
Include triglycerides, steroids,
phospholipids, and fat-soluble
vitamins.
Triglycerides most common type
of lipid in the diet, accounting for
about 95% of the total lipid intake.
If the fat is a liquid at room
temperature, it is referred to as an
oil.
o Fats are saturated if they only
have single covalent bonds
between carbon atoms.
o Fats are unsaturated if they
have one or more double
bonds.
o Mono-unsaturated have one
double bond.
o Polyunsaturated have two or
more double bonds.
Saturated fats are found in meat, dairy,
products, eggs, nuts, coconut oil, and palm
oil.
Monounsaturated fats include olive and
peanut oils.
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NUTRITION, METABOLISM, AND BODY TEMP. 1 st YR | ANAPHY

NUTRITION is the process by which food is taken into and used by the body; it includes digestion, absorption, transport, and metabolism.

  • The study of nutrition involves the study of the food and drink requirements for normal body function.
  • Nutrients are the chemicals taken into the body that provide energy and building blocks for new molecules.

NUTRIENTS IS DIVIDED TO (6)

MAJOR CLASSES:

1. CARBOHYDRATES

2. LIPIDS

3. PROTEINS

4. VITAMINS

5. MINERALS

6. WATER

  • A balanced diet consists of enough nutrients in the correct proportions to support normal body functions.
  • Essential nutrients are nutrients that must be ingested because the body cannot manufacture them- or it CANNOT manufacture them in adequate amounts.
  • The essential nutrients include certain amino acids, fatty acids, most vitamins, minerals, water, and some carbohydrates.

CARBOHYDRATES

  • Contain C, H, O
  • H:O is a 2:1 ratio Example: C6H12O
  • Include monosaccharides, disaccharides, and polysaccharides.
  • MONOSACCHARIDES – simple sugar ( sugar) Example: glucose and fructose
  • DISACCHARIDE – two (2) sugars Examples: glucose + fructose = sucrose glucose + galactose = lactose
  • POLYSACCHARIDE – many sugars Examples: starch, grain, vegetables, glycogen

TYPES OF CARBOHYDRATES

  1. Simple – no nutritional value; cause weight gain Examples: candy and soft drinks ✓ Recommended amount: sparingly
  2. Complex – fiber helps decrease colon cancer and heart disease. Examples: whole grains, pastas, rice, bread. ✓ Recommended amount: at every meal

FUNCTIONS OF CARBOHYDRATES

  • Short-term energy storage
  • Converted to glucose quickly
  • Glucose is used to make ATP (energy)
  • Brain cells require glucose

LIPIDS

LIPIDS - totally or partially insoluble in water.

  • Include triglycerides, steroids, phospholipids, and fat-soluble vitamins.
  • Triglycerides – most common type of lipid in the diet, accounting for about 95% of the total lipid intake.
  • If the fat is a liquid at room temperature, it is referred to as an oil. o Fats are saturated if they only have single covalent bonds between carbon atoms. o Fats are unsaturated if they have one or more double bonds. o Mono-unsaturated have one double bond. o Polyunsaturated have two or more double bonds. Saturated fats are found in meat, dairy, products, eggs, nuts, coconut oil, and palm oil. Monounsaturated fats include olive and peanut oils.

Polyunsaturated fats are found in fish, safflower, sunflower, and corn oils.

SATURATED & UNSATURATED

UNSATURATED – “better” for us; liquid at room temperature. SATURATED – “bad” for us; solid at room temperature. TRANS FATTY ACIDS – processed fats and oils ▪ raise LDL and lower HDL ▪ increase heart disease

CHOLESTEROL

Cholesterol – a steroid ❖ high concentration in brain, liver, egg yolks, whole milk, cheese, butter, meats. LDL Cholesterol – low density lipoprotein ❖ “bad” cholesterol ❖ carries cholesterol from liver to cells HDL Cholesterol – high density lipoprotein ❖ “good” cholesterol ❖ carries cholesterol from cells to liver ❖ increase HDL through exercise

LIPIDS AND DIET

✓ Recommended amount: sparingy for saturated fats

  • cholesterol 300 mg/day (1 egg yolk) Lipids can: cause weight gain and heart disease; increase risk of colon and pancreatic cancer.

REDUCING FAT AND CHOLESTEROL

✓ eat poultry, fish, and beans ✓ eat vegetables and fruits high in fiber ✓ use herbs and spices for seasonings ✓ broil, bake, grill ✓ limit creams and butter ✓ avoid processed cheese, egg yolks, liver

FUNCTIONS OF LIPIDS

  • long term energy storage
  • insulates against heat loss
  • protective cushion for organs
  • cholesterol is part of cell membrane structure

PROTEINS

PROTEINS - chains of amino acids and are found in most of the plant and animal products eaten.

  • Proteins in the body are constructed of 20 different kinds of amino acids, and divided into (2) groups: ESSENTIAL and NON-ESSENTIAL amino acids.
  • The body cannot synthesize essential amino acids, so they must be obtained in the diet. o The nine essential amino acids: Histidine, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Threonine, Tryptophan, Valine.
  • Complete protein food contains all nine essential amino acids in the needed proportions, whereas an incomplete protein food does not.
  • Animal proteins tend to be complete proteins, whereas plant proteins tend to be incomplete.
  • Plant-based foods = soy, quinoa are sources of complete proteins. Amino acids aren’t stored so a daily supply is required. ✓ Recommended amount: 1 to 2 servings dairy group; 1 to 3 servings nuts/beans; 0 to 2 servings fish, poultry, eggs; red meat sparingly ✓ Serving 2 to 3 oz.

FUNCTIONS OF PROTEINS

  • used to make skin, hair, nails, muscles
  • hemoglobin
  • act as enzymes
  • immune system functions
  • muscle contractions (actin & myosin)
  • part of cell membrane

VITAMINS

  • Organic molecules in small quantities in food needed for metabolism.
  • Balance diet gives body variety of vitamins.
  • Absence of vitamins results in deficiency diseases.
  • Fat or water soluble.
  • Fat soluble vitamins include vitamins A, D, E, and K
  • Water soluble include the B-complex and C

ATP

  • Adenosine Triphosphate
  • Energy carrier
  • Energy is released when ATP is broken down.
  • Some ATP is produced in the cytoplasm.
  • Most ATP is produced in the mitochondria.

CARBOHYDRATE METABOLISM

  • Monosaccharides are the breakdown products of carbohydrate digestion, with the most important being glucose.
  • Any excess glucose in the blood following a meal can be used to form glycogen, or it can be partially broken down and the components used to form lipids.
  • The metabolism of carbohydrates involves anaerobic and aerobic respiration with glycolysis, aerobic respiration for the citric acid cycle and ETC.

GLYCOLYSIS

  • Glycolysis is a series of chemical reactions that occurs in the cytoplasm.
  • It results in the breakdown of glucose to two pyruvic acid molecules.
  • When glucose is converted to pyruvic acid, two ATP molecules are used and four ATP molecules are produced, for a net gain of two ATP molecules.

ANAEROBIC RESPIRATION

  • Anaerobic respiration – breakdown of glucose in the absence of O2.
  • In human cells, anaerobic reults in the production of 2 molecules of lactate and 2 molecules of ATP.

DIVIDED INTO 2 PHASES:

GLYCOLYSIS – produce 2 pyruvic acid molecules, 2 ATP, and 2 NADH. LACTATE FORMATION – pyruvic acid is converted to lactic acid and converted to lactate. (ionized form of lactic acid)

AEROBIC RESPIRATION

Electron Transport Chain – series of electron-transport molecules attached to the inner mitochondrial membrane.

  • Electrons are transferred from NADH and FADH2 to the electron-transport carriers, and H+ is released into the inner mitochondrial compartment.
  • Because of an increased H+ concentration in the outer compartment, the H+ passes by diffustion back into the inner compartment.
  • The H+ passes through channels in the inner mitochondrial membrane that couple the movement of the H+ to ATP production.
  • Without O2 to accept the H+ and electrons, the citric acid cycle and the electron-transport chain cannot function.

LIPID METABOLISM

  • Triglycerides are body’s main energy storage molecules.
  • Between meals triglycerides are broken down into fatty acids and glycerol.
  • Metabolism occurs in mitochondria.
  • 2 carbons are removed for fatty acids to form acetyl-CoA.
  • In the liver, 2 Acetyl-CoaA combines to form ketones. Too many ketones = acidosis in blood.

PROTEIN METABOLISM

  • Proteins digested into amino acids.
  • Amino acids are used to make needed proteins.
  • Amino acids can be converted ito pyruvic acid and acetyl COA and can be metabolized to yield ATP.
  • Metabolism results in ammonia which is toxic in cells. Will be converted by the liver to become urea.

METABOLIC STATES

ABSORPTIVE STATE – period immediately after a meal; 4 hrs after meal. ✓ Glucose goes to cells and the remaining glucose is converted into glycogen/fats. ✓ Glycogen in liver and skeletal muscles, fats into adipose. POSTABSORPTIVE STATE – late in morning, afternoon, or night after absorptive state. ✓ Blood glucose levels maintained by converting molecules to glucose. (NORMAL BG range between 70 and 110 mg/dL) ✓ First source glucose is liver where glycogen is stored. ✓ Glycogen supply can provide glucose for abt 4 hrs. ✓ Fats as energy source – can partly eleminate the need to use glucose for energy, resulting in reduced glucose removal from the blood and maintain blood glucose.

METABOLIC RATE

  • M.R – total amount of energy produced and use in body per unit of time.
  • Basal Metabolic Rate – energy needed to keep resting body functional.
  • Used to determine number (amount) of kilocalories need per day.

BODY TEMPERATURE REG.

  • Average body temp. is 98.6 F or 37 degrees Celsius.
  • Maintained by balancing heat input with heat loss. - Amount of heat exchanged between environment and body is determined by difference in temperatures. Temperature regulation occurs by dilation and constriction of blood vessel in the skin. - Sweat glands & skeletal muscles - Homeostasis occurs by negative feedback system. - HYPOTHALAMUS IS THE CONTROL CENTER MONITORING BODY TEMPERATURE.

MECHANISMS FOR BODY HEAT LOSS

RADIATION – gain or loss of heat as infrared energy between 2 objects not in physical contact. Ex: sun, hot sand, snow CONDUCTION – exchange of heat between objects that in direct contact. Ex: contact of the bottom of the feet and the ground. CONVECTION – transfer of heat between body and air or water. Ex: cool breeze over body. EVAPORATION – conversion of water from liquid to gas. Ex: water from body surface.