Docsity
Docsity

Prepare for your exams
Prepare for your exams

Study with the several resources on Docsity


Earn points to download
Earn points to download

Earn points by helping other students or get them with a premium plan


Guidelines and tips
Guidelines and tips

MOL114 Midterm; Semester 1 (University of Notre Dame), Exams of Medicine

1. Intravascular hemolysis causes: Increased serum levels of LDH 2. Non-competitive inhibition: Decreases V-max 3. TCA cycle involves both synthesis & degradation, it is called: a. Amphibolic b. Catabolic c. Anabolic d. Bipolar e. Amphipathic 4. The conversion of pyruvate to Acetyl-CoA: a. Involves lipoic acid b. Catalyzed by pyruvate decarboxylase 5. A scientist wants to create a transgenic mouse that can digest cellulose. To do that, he needs to insert a gene for: a. β (1-4) glucosidase b. β (1-6) glucosidase c. α (1-6) & β (1-4)

Typology: Exams

2024/2025

Available from 07/14/2025

Testfix
Testfix 🇬🇧

4.1

(21)

755 documents

1 / 8

Toggle sidebar

This page cannot be seen from the preview

Don't miss anything!

bg1
MOL114 Midterm; 1st Semester
Multiple Choice Questions -40-
1. Intravascular hemolysis causes:
Increased serum levels of LDH
2. Non-competitive inhibition:
Decreases V-max
3. TCA cycle involves both synthesis & degradation, it is called:
a. Amphibolic
b. Catabolic
c. Anabolic
d. Bipolar
e. Amphipathic
4. The conversion of pyruvate to Acetyl-CoA:
a. Involves lipoic acid
b. Catalyzed by pyruvate decarboxylase
5. A scientist wants to create a transgenic mouse that can digest cellulose. To
do that, he needs to insert a gene for:
a.
β (1-4) glucosidase
b. β (1-6) glucosidase
c.
α
(1-6) & β (1-4)
6. A patient, diagnosed with Hepatitis A, has malaise, fatigue. He has:
a. Raised serum aspartate aminotransferase
b. Raised LDH
7. Which of the following inhibits both the ketoglutarate dehydrogenase
complex and succinate dehydrogenase complex?
a. NADH
b. ATP
c. Ca++
pf3
pf4
pf5
pf8

Partial preview of the text

Download MOL114 Midterm; Semester 1 (University of Notre Dame) and more Exams Medicine in PDF only on Docsity!

MOL114 Midterm; 1

st

Semester

Multiple Choice Questions - 40-

  1. Intravascular hemolysis causes: Increased serum levels of LDH
  2. Non-competitive inhibition: Decreases V-max
  3. TCA cycle involves both synthesis & degradation, it is called: a. Amphibolic b. Catabolic c. Anabolic d. Bipolar e. Amphipathic
  4. The conversion of pyruvate to Acetyl-CoA: a. Involves lipoic acid b. Catalyzed by pyruvate decarboxylase
  5. A scientist wants to create a transgenic mouse that can digest cellulose. To do that, he needs to insert a gene for: a. β (1-4) glucosidase b. β (1-6) glucosidase c. α (1-6) & β (1-4)
  6. A patient, diagnosed with Hepatitis A, has malaise, fatigue. He has: a. Raised serum aspartate aminotransferase b. Raised LDH
  7. Which of the following inhibits both the ketoglutarate dehydrogenase complex and succinate dehydrogenase complex? a. NADH b. ATP c. Ca++
  1. Which of the following enzymes provide the bacteria with NAD+? Lactate dehydrogenase
  2. What type of inhibition is observed when allopurinol inhibits xanthine oxidase? a. Non-competitive inhibition b. Feedback inhibition c. Competitive
  3. Given delta G = + 3.4 , which of the following is true? At standard conditions the reaction will not occur spontaneously
  4. In reaction where A was changed into B, delta G= 3.2, and we had equal concentrations of both, which of the following could be true? a. There is no net chemical change b. It favors a backward reaction c. More reactants than products
  5. Which of the following is true regarding the mitochondria? a. It has an impermeable inner membrane to molecules and ions b. Outer membrane is highly folded c. Glycolytic enzymes are present in the matrix
  6. A patient was advised to eat less glucose containing food and start exercising, which of the following would happen? a. Increase uptake of glucose by liver b. Increase Insulin dependent glucose transporter (GLUT4)
  7. What does the heat/energy present as? a. Enthalpy b. Entropy
  8. What are arabinose and ribose: Epimers
  1. Hemolytic anemia is caused by which of the following? Mutation in pyruvate kinase
  2. Which of the following enzymes is responsible for the rate limiting step? PFK- 1
  3. Which of the following will form a high energy product & reduce NAD+ in glycolysis? a. Glyceraldehyde-3-phosphate dehydrogenase b. Lactate dehydrogenase
  4. A 28-year-old male develops diabetes, as noted by constant, mildly elevated hyperglycemia. His father had similar symptoms at the same age as did paternal grandmother. This patient is not obese, does not have hypertension, does not have dyslipidemia, and does not have antibodies directed against islet cells. This alteration in glucose homeostasis may be due to mutation in which of the following enzymes? a. Pancreatic glucokinase b. Pancreatic hexokinase c. Liver glucokinase d. Muscle hexokinase e. Intestinal glucokinase f. Glyceraldehyde dehydrogenase
  5. Retonene is a nitroprusside that inhibits an oxidative phosphorylation complex: Binding to a specific site in the chain
  6. Which of the following markers is the most precise in showing the condition of myocardial infarction: a. CK-MB b. Total CK c. Ratio of CK MB/ Total CK
  1. In a given table, what is the Km that gives ½ of Vmax? a. 0. b. 1. c. 0.
  2. Which reaction takes place to create a bond between two monosaccharides: a. oxidation b. reduction c. hydrolytic d. proteolytic e. condensation
  3. Given Vmax= 20 Mmol/min, Km= 5 x 10^-6 M, substrate concentration = 5x10^-4 M. What is the velocity of the reaction? a. 10 b. 15 c. 25 d. 30 e. 20
  4. If the reaction is in equilibrium, which of the following is correct? Delta G=
  5. Why do we phosphorylate glucose? To keep it inside the cell
  1. Which of the following from steps inactivates the committed step in glycolysis & activates the synthesis of ATP: Citrate
  2. Which of the following is a 5 carbon that is converted to a 4 carbon molecule by the release of CO2: a. α ketoglutarate b. Citrate c. Oxaloacetate d. Malate
  3. Nitroprusside inhibits which complex? a. PDH complex b. Cytochrome b/c c. Cytochrome a/a d. Succinate dehydrogenase e. NADH dehydrogenase complex
  4. What does an uncoupler do? Prevents exchange of electrons along the inner membrane of mitochondria The exam committee of the 9 th^ batch