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GI Liver and Pancreatic cancers-Medicine, Lecture notes of Medicine

This document provides an in-depth overview of gastrointestinal (GI), liver, and pancreatic cancers, focusing on hepatocellular carcinoma, cholangiocarcinoma, pancreatic adenocarcinoma, and bowel cancer. It outlines risk factors, clinical features, diagnostic investigations (e.g., tumor markers, CT scans, colonoscopy), and treatment options, including surgical procedures like the Whipple procedure and hemicolectomy. The guide also discusses screening methods, such as fecal immunochemical tests (FIT), and the importance of staging cancers using the TNM system. This resource is essential for understanding the diagnosis, management, and prognosis of these cancers in clinical practice.

Typology: Lecture notes

2024/2025

Available from 03/12/2025

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charles-khama 🇮🇹

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3/12/25, 1:58 PM about:blank Gl Liver and Pancreatic cancers GI, Liver and Pancreatic cancers Liver cancer ‘Two main types: 1, Hepatocellular carcinoma (80%) 2. Cholangiocarcinoma (20%) Risk factors: + Viral hepatitis B and C * Alcohol + NAFLD * Other chronic liver disease — Patients with chronic liver disease are screened for HCC Clinical features: + Weight loss * Abdominal pain * Anorexia * Nausea and vomiting * Jaundice + Pruritus —+ Cholangiocarcinoma often presents with painless jaundice like pancreatic cancer Investigations: Gl, Liver and Pancreatic eancers 15