[CYTOGENETICS]
PEDIGREE & GENETIC COUNSELING
PEDIGREE SHOWS TRAIT & DISEASE INHERITANCE
AUTOSOMAL RECESSIVE
AUTOSOMAL DOMINANT
X-LINKED RECESSIVE
X-LINKED DOMINANT
Y-LINKED
MITOCHONDRIAL
CHARACTERISTICS
two allele
one copy
father NO TO son
father TO son
males, female equal
influence phenotype
influence phenotype
father TO daughter
father TO ALL daughter
holandric inheritance
TO ALL son & daughter
heterozygous parents no condition, carry allele
no symptom, until later in life / after reproductive age
males more affected
neither parent has trait, one child inherits
unknown affected, child inherits
after puberty
after puberty
DISORDERS
cystic fibrosis
freckles
hemophilia
structural genes
basta ung mga 3 letters,
super dami nila
heteroplasmy
tay-sachs
polydactylism
red-green color blindness
incontinentia pigmenti
(skin lesions)
electron transport
maple syrup urine
huntington’s disease
x-linked ichthyosis
x-linked rickets
(bones soften/deform)
oxidative phosphorylation
process (neuro/myopathies)
phenylketonuria
